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艾美捷科技代理Dovetail Genomics品牌全系列产品


Dovetail Genomics公司成立于2013年,是染色体级别基因组组装领域的创新者,Dovetail Genomics公司正在解决包括染色质拓扑结构分析、大小体细胞变异检测、从头染色体组装和单倍型定相在内的复杂问题。Dovetail Genomics通过其专利的Hi-C/Omini-C技术,填补了短读长测序无法完成高质量组装的空白,产品广泛应用于表观遗传学、发育生物学、癌症研究、进化生物学、传染病等领域。


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Dovetail Genomics公司的产品


Dovetail Assay
ApplicationLinkPrep™Micro-CHiChIPPan PromoterOmni-C
Genetic VariationLarge Structural Variant
Detection Genotyping




Genotyping



Haplotype Phasing


Chromatin TopologyTargeted Enhancer-
Promoter Interactions





Nucleosome-level
Chromatin Topology




Whole Genome Rapid
High-Resolution Topology




Protein Anchored
Topology




Genetic Genome AssemblyGenome Scaffolding


Hybrid Capture Compatible


Dovetail® LinkPrep™ Kit

采用Tn5转座酶实现染色质均匀片段化,确保捕获无偏差的完整染色质三维构象。产品特点:

● 单日工作流:样本→测序文库仅需8小时(传统Hi-C需3-5天)

● 零专用设备:兼容常规分子生物学实验室

● 实现单倍型定相组装(Haplotype-resolved)

● 同步捕获全谱变异:SNV/InDel/CNV/SV(灵敏度达95%)

● 适用于基因组拓扑结构、遗传变异、基因组组装


Dovetail® Micro-C Kit

获取核小体分辨率的三维基因组图谱,针对需要单核小体级别精细拓扑图谱的研究(解析150-200 bp染色质构象),本技术可逐层解锁基因组三维结构。其在1千碱基对(kbp)以下分辨率呈现的高信噪比特性,使研究者能够以显著降低的成本构建高质量的染色质互作矩阵。产品特点:

● 核小体级精度:直接解析 150-200 bp染色质基本单元(单核小体)的空间构象,突破传统Hi-C技术分辨率限制(通常>1 kbp)

● 超高信噪比优势:在亚千碱基级别消除背景噪音,精确捕获微尺度拓扑关联域(如增强子-启动子互作)

 成本降低:相较冷冻电镜或ChIA-PET等方法,实验成本下降60-80%; 矩阵数据质量提升(矩阵信噪比 > 95%,传统方法约70-85%)


Dovetail® Pan Promoter Kit

专为绘制“基因启动子-调控元件”三维互作图谱设计,通过靶向富集技术实现高分辨率、低成本的染色质构象分析。


Dovetail® HiChIP Kit

抗体导向的精准三维基因组捕获系统,融合Hi-C空间架构捕获与ChIP靶向富集技术,实现对特定蛋白(如CTCF、Cohesin、组蛋白修饰)介导的染色质互作进行纳米级分辨率解析。产品特点:

 分辨率:200 bp(单核小体水平)

 灵敏度:检测低频互作(≥5个细胞中1次事件)

 特异性:抗体结合位点富集度 >100X;非特异性背景 <2%

 样本兼容性:冰冻组织、FFPE样本、单细胞悬液


Dovetail® Omni-C® Kit

通过Tn5转座酶同时捕获染色质空间互作与酶切位点信息,核心优势:

● 高分辨率:精准解析拓扑关联结构域(TADs)、染色质环

 多组学整合:单次实验同步检测染色质构象+基因变异(SNV/InDel/CNV/SV)

 样本兼容性:支持微量样本(>50mg组织/ >10,000个细胞)


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艾美捷科技代理42 life sciences品牌全系列产品


42 life sciences是一家位于德国北部不来梅港的中小型企业。42 life sciences专注于开发和生产用于免疫组化(IHC)及原位杂交(ISH)应用的创新试剂。公司的核心优势在于拥有经验丰富的生物技术专家团队,确保产品开发高效聚焦,同时以可靠且具成本效益的方式进行生产。所有研发与制造流程均在我们自有设施中严格遵循EN ISO9001和EN ISO 13485标准执行。

42 life sciences公司的产品与服务包括:免疫组化与原位杂交创新试剂;外包生物缓冲液及试剂的生产业务。


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▎42 life sciences产品列表

分类品名产品描述货号规格
Chromogens for HRPAEC Solution IHC (ready-to-use)AEC (3-Amino-9-Ethylcarbazole) is a commonly used chromogen for immunohistochemical (IHC) procedures supplied in one liquid component.S-99012-100;S-99012-1000100ml;1000ml
Chromogens for HRPAEC Solution ISH (ready-to-use)AEC (3-Amino-9-Ethylcarbazole) is a commonly used chromogen for chromogenic in situ hybridization (CISH) procedures supplied in one liquid component.S-99010-500;S-99010-1000500ml;1000ml
Chromogens for HRPDAB Solution Set (2 components)DAB (3,3‘-diaminobenzidine) is a widely used chromogen in immunohistochemical and immunoblotting applications.S-99014-103;S-99014-1030103ml;1030ml
Chromogens for HRPHRP-Green Solution Set (2 components)The HRP-Green Solution Set is a new chromogen used in immunohistochemical and chromogenic in situ hybridization applications.S-99056-103;S-99056-1030103ml;1030ml
Chromogens for HRPHRP-Green Solution Set (MxE)The HRP-Green Solution Set (MxE) is a unique chromogen used in immunohistochemical and chromogenic in situ hybridization applications that is mixable in equal parts.S-99070-100;S-99070-2000100ml;2000ml
Chromogens for HRPAP-Red Solution Set IHC (2 components)The AP-Red Solution Set IHC is a chromogen used in immunohistochemical applications.S-99065-103103ml
Chromogens for HRPAP-Red Solution Set ISH (2 components)The AP-Red Solution Set ISH is a chromogen used in chromogenic in situ hybridization applications.S-99061-10301030ml
Chromogens for HRPNBT/BCIP Solution (ready-to-use)The NBT/BCIP Solution is a chromogen used in immunohistochemical and chromogenic in situ hybridization applications.S-99064-500500ml
CounterstainsMayer`s Hematoxylin Solution (ready-to-use)Mayer’s Hematoxylin Solution is a staining reagent for histological applications.S-99025-10001000ml
CounterstainsNuclear Blue Solution (ready-to-use)Nuclear Blue Solution is a hematoxylin based reagent for counterstaining applications in in situ hybridization (ISH) and immunohistochemistry (IHC) procedures using common chromogens like AEC and DAB.S-99035-10001000ml
CounterstainsNuclear Fast Red Solution (ready-to-use)Nuclear Fast Red Solution is designed for use as a counterstaining solution in immunohistochemistry (IHC) procedures using common chromogens like BCIP/NBT.S-99031-10001000ml
CounterstainsNuclear Red Solution (ready-to-use)Nuclear Red Solution is a nuclear fast red (a.k.a. Kernechtrot) based reagent for counterstaining applications in in situ hybridization (ISH) and immunohistochemistry (IHC) procedures.S-99033-500;S-99033-1000500ml;1000ml
CounterstainsNuclear Green Solution (ready-to-use)Ready-to-use Nuclear Green Solution optimized for the use in immunohistochemical (IHC) and in situ hybrididzation (ISH) procedures. Suitable for aqueous and non- aqueous mountants.S-99104-10001000ml
Ancillary Reagents1% BSA Ab Diluent (ready-to-use)The 1% BSA Ab Diluent is a stabilizer and diluent for all antibodies routinely used in immunohistochemistry (IHC) and in situ hybridization (ISH) applications.S-99068-10001000ml
Ancillary Reagentsone4all-Antibody Stabilizer (ready-to-use)The one4all-Antibody Stabilizer is a unique stabilizer for all antibody-enzyme conjugates routinely used in immunohistochemistry (IHC) and in situ hybridization (ISH) applications as well as in ELISA.S-99030-10001000ml
Ancillary ReagentsPepsin Solution (ready-to-use)Pepsin is a commonly used digestive enzyme for immunohistochemical (IHC) and in situ hybridization (ISH) procedures.S-99003-50;S-99003-500;S-99003-100050ml;500ml;1000ml
Ancillary ReagentsPepsin Solution for Cytology (ready-to-use)Pepsin Solution for Cytology is a digestive enzyme solution used in in situ hybridization (ISH) procedures in cytology specimens.S-99053-500;S-99053-1000500ml;1000ml
Ancillary ReagentsProteinase K Solution (ready-to-use)The Proteinase K Solution is specifically designed for use in the pretreatment of formalin-fixed tissue for in situ-hybridization (ISH) procedures.S-99080-100100ml
Ancillary ReagentsDuraTect™ DAPI/Antifade Solution (ready-to-use)The DuraTect™ DAPI/Antifade Solution is a refrigerator-stable formula for preserving fluorescence.S-99081-10;S-99081-100;S-99081-50010ml;100ml;500ml
Ancillary ReagentsDuraTect™ DAPI/Antifade Solution "ultra" (ready-to-use)The DuraTect™ DAPI/Antifade Solution "ultra" is a refrigerator-stable formula for preserving fluorescence.S-99098-5050ml
Ancillary ReagentsCOT-DNA, human (10mg/ml)The COT fraction of human genomic DNA predominantly consists of rapidly annealing repetitive sequences.S-99040-1;S-99040-10;S-99040-501mg;10mg;50mg



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艾美捷科技代理PRIMACYT品牌全系列产品


PRIMACYT是专注于体外技术领域的一家德国公司。PRIMACYT公司致力于通过高度模拟人体生物学特性的细胞培养平台,提供肝脏、皮肤和血液衍生的生物学检测系统,广泛应用于人类和动物健康以及环境安全测试领域。公司核心业务涵盖肝细胞、肝脏亚细胞组分、皮肤组织、血液衍生产品及细胞培养基等关键技术产品。


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▍PRIMACYT产品线

人和动物源的原代肝细胞及肝脏亚细胞组分(部分产品列表)

PRIMACYT提供全球最大的肝脏衍生体外系统产品组合,包括高质量的原代肝细胞及肝脏亚细胞组分,细胞来源涵盖人类、啮齿动物、农场动物,鸟类及鱼类。这些细胞可用于药物代谢、毒性研究和药物筛选。

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品名货号产品描述
Human hepatocytesHHCSHuman Hepatocytes Cryopreserved for use in Suspension
Human hepatocytesHHCPHuman Hepatocytes Cryopreserved Plateable
Human hepatocytesHHCP-IHuman Hepatocytes Cryopreserved Plateable, Cytochrome P450 inducible
Human non-parenchymal liver cellsHLSECHuman liver sinusoidal endothelial cells cryopreserved
Cryopreserved Mouse HepatocytesMHCP-I-3DMouse Hepatocytes Cryopreserved Plateable, Cytochrome P450 inducible, Suitable for 3D culture
Cryopreserved Mouse HepatocytesMHCP-IMouse Hepatocytes Cryopreserved Plateable, Cytochrome P450 inducible
Cryopreserved Mouse HepatocytesMHCPMouse Hepatocytes Cryopreserved Plateable
Wistar Han Rat Liver CellsWH-RHCP-I-3DWistar Han rat hepatocytes cryopreserved plateable, Cytochrome P450 inducible, suitable for 3D spheroid cultures
Wistar Han Rat Liver CellsWH-RHCP-IWistar Han rat hepatocytes cryopreserved plateable, Cytochrome P450 inducible
Wistar Han Rat Liver CellsWH-RLKCWistar Han rat liver Kupffer cells cryopreserved
Wistar Han Rat Liver CellsWH-RLSCWistar Han rat liver Stellate cells cryopreserved
Sprague Dawley Rat Liver CellsSD-RHCP-ISprague Dawley rat hepatocytes cryopreserved plateable, Cytochrome P450 inducible
Sprague Dawley Rat Liver CellsSD-RLKCSprague Dawley rat liver Kupffer cells cryopreserved
Sprague Dawley Rat Liver CellsSD-RLNPCSprague Dawley rat liver nonparenchymal cells cryopreserved
Cryopreserved Rabbit HepatocytesNZL-RabHCP-INew Zealand White Rabbit Hepatocytes Cryopreserved Plateable, Cytochrome P450 inducible
Cryopreserved Rabbit HepatocytesRabHCP-IDomestic Rabbit Hepatocytes Plateable, Cytochrome P450 inducible
Cryopreserved Cynomolgus HepatocytesCHCP-I-3DCynomolgus hepatocytes cryopreserved plateable Cytochrome P45o inducible and 3D (Spheroid culture) qualified



● 原代皮肤细胞和人离体皮肤组织

PRIMACYT提供人源和动物源的皮肤成纤维细胞和角质形成细胞的原代皮肤细胞,这些细胞可应用于皮肤毒性研究、药物递送系统评估和皮肤相关疾病模型的研究。具体应用包括:局部药物的表征;生物杀菌剂、农业化学品的安全评估;化妆品成分的安全性评估;基于物质的医疗器械分类。


品名货号产品描述
Skin tissues (human)H-skinHuman Skin
Skin discs & dermatomed skinH-skin disc-
Skin discs & dermatomed skinH-skin sheet-
Human and Cynomolgus FibroblastsNHDF-ADNormal Human Dermal Fibroblasts, adult donor
Human and Cynomolgus FibroblastsNHDF-JFNormal Human Dermal Fibroblasts, juvenile foreskin
Human and Cynomolgus FibroblastsNCDFNormal Cynomolgus Dermal Fibroblasts
KeratinocytesNHEK-JFNormal Human Epidermal Keratinocytes, juvenile foreskin donor


● 血液制品

包括来自健康人类和动物来源的血液制品,如全血、血浆、外周血单核细胞、血沉棕黄层等。这些血液制品可广泛应用于血液相关疾病的研究、免疫反应评估以及其他毒理学研究。

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品名货号产品描述
PMBC - Peripheral Blood Mononuclear Cell (human)HPBMChuman PBMC
PMBC - Peripheral Blood Mononuclear Cell (rat)SD-RPBMC-poolSprague Dawley Rat PBMC
PMBC - Peripheral Blood Mononuclear Cell (rat)SD-RPBMC-single donorSprague Dawley Rat PBMC
PMBC - Peripheral Blood Mononuclear Cell (rat)WH-RPBMC-poolWistar Han Rat PBMC
PMBC - Peripheral Blood Mononuclear Cell (rat)WH-RPBMC-single donorWistar Han Rat PBMC
PMBC - Peripheral Blood Mononuclear Cell (mouse)MPBMC-poolmouse PBMC


 实验消耗品(Consumables)

PRIMACYT提供定制化的细胞培养基、试剂盒和细胞培养板,支持各种细胞的生长和功能维持。PRIMACYT的培养基专为优化细胞活性和功能设计,适用于不同动物来源的肝细胞的解冻、贴壁和培养,满足长期培养、药物筛选和毒性评估等多种实验需求。


分类货号
产品描述
3D Hepatocytes Maintenance Medium3D-HMM-500S3D-Hepatocyte Maintenance Medium
3D Hepatocytes Maintenance Medium3D-HMM-5003D-Hepatocyte Maintenance Medium
3D Hepatocytes Maintenance Medium3D-HMM-2503D-Hepatocyte Maintenance Medium
Long Term Hepatocyte Culture Medium (HHMM)HHMM-500SHuman Hepatocyte Maintenance Medium
Long Term Hepatocyte Culture Medium (HHMM)HHMM-500Human Hepatocyte Maintenance Medium
Long Term Hepatocyte Culture Medium (HHMM)HHMM-250Human Hepatocyte Maintenance Medium
Long Term Hepatocyte Culture Medium (HHMM)ACF-HHMM-500SAnimal Component Free Human Hepatocyte Maintenance Medium
Long Term Hepatocyte Culture Medium (HHMM)ACF-HHMM-500Animal Component Free Human Hepatocyte Maintenance Medium
Long Term Hepatocyte Culture Medium (HHMM)ACF-HHMM-250Animal Component Free Human Hepatocyte Maintenance Medium
Long Term Hepatocyte Culture Medium (HHMM)FHM-
Long Term Hepatocyte Culture Medium (HHMM)FGM-500-
Short Term Hepatocyte Culture Medium (HM)HM-500Hepatocyte Medium
Short Term Hepatocyte Culture Medium (HM)HM-250Hepatocyte Medium
Thawing and Plating KitsPTK-1Thawing and Plating of Cryopreserved Hepatocytes
Thawing and Plating KitsPTK-2Thawing and Plating of Cryopreserved Hepatocytes from Rat and Minipig
Thawing and Plating KitsPTK-NPCThawing and Plating of Cryopreserved Non-parenchymal liver cells
Thawing and Plating KitsTK-1Thawing Kit Cryopreserved Mammal Hepatocytes Suspension Assays
Thawing and Plating KitsTK-FHSAThawing Kit Cryopreserved Fish Hepatocytes Suspension Assays
Collagen ProductsCCP-06Cell culture plate coated with rat tail collagen,6well, Package of 5
Collagen ProductsCCP-12Cell culture plate coated with rat tail collagen,12well, Package of 5
Collagen ProductsCCP-24Cell culture plate coated with rat tail collagen,24well, Package of 5
Collagen ProductsCCP-96Cell culture plate coated with rat tail collagen,96well, Package of 5
Collagen ProductsRTC-100Rat Tail Collagen Type I,3mg/ml, 100 ml
BIOFLOAT™ ULA platesBioFloat™ SeriesBioFloat™ 96 well plate,ready to use


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艾美捷科技代理Rigaku Reagents品牌。

Rigaku Reagents 是 Rigaku 集团旗下的一家子公司,专注于为X射线晶体学领域提供高质量的化学试剂和工具。Rigaku 集团是全球知名的科学仪器制造商,尤其在X射线分析技术领域具有领先地位。Rigaku Reagents 的主要目标是支持科学家在蛋白质晶体学、材料科学和其他相关领域的研究,提供用于晶体生长、样品制备和分析的高质量试剂和耗材。热门产品包括:Wizard Classic/Wizard Cryo 系列蛋白结晶筛选试剂盒,结晶板,结晶工具,和 PEG3350、PEG6000、PEG8000 等试剂。主要产品类别为:

(1)晶体生长试剂:Rigaku Reagents 提供多种用于蛋白质和小分子晶体生长的试剂,包括结晶筛选试剂盒、缓冲液、沉淀剂和添加剂。这些试剂经过严格的质量控制,确保实验的可重复性和可靠性。

(2)结晶筛选试剂盒:公司提供多种结晶筛选试剂盒,如 Crystal Screen、Index Screen 和 SaltRx Screen,适用于不同类型的晶体生长实验。这些试剂盒设计科学,能够显著提高晶体生长的成功率。

(3)蛋白质结晶工具:提供用于蛋白质结晶的耗材和设备,如结晶板、密封膜和样品支架。这些工具与 Rigaku 的X射线衍射仪兼容,支持从晶体生长到数据分析的全流程。

(4)小分子结晶试剂:为小分子晶体学研究提供高质量的试剂和工具,支持药物开发、材料科学等领域的研究。

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艾美捷科技代理Synthelis Biotech品牌全系列产品


Synthelis Biotech是一家法国公司,专注于蛋白质的生产、纯化与表征,公司致力于助力疫苗、生物制剂、酶、工程蛋白、诊断工具以及高通量分子或配体筛选技术的开发。Synthelis Biotech提供经过验证的蛋白质,其活性和纯度均根据特定应用(候选药物筛选、抗体与疫苗开发、结构生物学、体外诊断、蛋白质载体化)量身定制。Synthelis Biotech专利的无细胞技术使客户能够从不同蛋白家族(GPCRs、离子通道、转运蛋白等)和不同形式(蛋白脂质体、纳米盘、去垢剂溶解形式或可溶形式)中选择合适的蛋白质。凭借其专利技术,Synthelis 能够在数小时内合成各类蛋白质:包括膜蛋白、毒性蛋白、修饰蛋白等,应用于药物筛选、疫苗与抗体开发、结构生物学以及体外诊断等领域。同时可按需进行修饰(荧光或同位素标记、非天然氨基酸掺入、截短或突变形式等)。


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▍Synthelis Biotech产品列表


分类品名ProteinOriginFormatReferenceQuantity分子量
Viral ProteinsE1Envelop protein 1Hepatitis C virusProteoliposomePL01110µg, 20µg, 50µg, 100µg, 200µg, 500µg21 kDa
Viral ProteinsE2Envelop protein 1Hepatitis C virusProteoliposomePL01010µg, 20µg, 50µg, 100µg, 200µg, 500µg21 kDa
Viral ProteinsN-proteinNucleocapsid Protein (COVID-19)SARS-Cov 2 virusSolubleS-14410µg, 20µg, 50µg, 100µg, 200µg, 500µg47,7 kDa
Viral ProteinsF5LVaccinia virus major membrane proteinVaccinia virusProteoliposomePL00710µg, 20µg, 50µg, 100µg, 200µg, 500µg39.0 kDa
Viral ProteinsHCV p7Hepatitis C virus P7HCV virusProteoliposomePL04210µg, 20µg, 50µg, 100µg, 200µg, 500µg7 kDa
GPCRsAPJ/ARApelin ReceptorHumanProteoliposomePL06110 µg, 50 µg ,100 µg44.7 kDa
GPCRsB2RBradykinin receptor 2HumanProteoliposomePL08010 µg, 50 µg ,100 µg47.0 kDa
GPCRsBRBacteriorhodopsinBacteriaProteoliposomePL02710 µg, 50 µg ,100 µg29.4 kDa
GPCRsCCR1C-C chemokine receptor type 1HumanProteoliposomePL02110 µg, 50 µg ,100 µg43.7 kDa
GPCRsCCR2aC-C chemokine receptor type 2, isoform aHumanProteoliposomePL02210 µg, 50 µg, 100 µg44.5 kDa
GPCRsCCR2bC-C chemokine receptor type 2, isoform bHumanProteoliposomePL02310µg, 20µg,100 µg, 200 µg42 kDa
GPCRsCCR5C-C chemokine receptor type 5HumanProteoliposomePL02410µg, 20µg ,100 µg , 200 µg, 500 µg,bulk40 kDa
GPCRsCXCR4C-X-C chemokine receptor type 4HumanProteoliposomePL01610 µg, 50 µg, 100 µg43 kDa
GPCRsCXCR4-DetergentC-X-C chemokine receptor type 4HumanDetergentD01625µg ,100 µg ,500 µg,bulk40 kDa
GPCRsGLP1RGlucagon-like peptide 1 receptorHumanProteoliposomePL06710 µg, 50 µg, 100 µg55.5 kDa
GPCRsGPR50G-protein coupled receptor 50HumanProteoliposomePL09510 µg, 50 µg, 100 µg67.4 kDa
GPCRsGPR54G-protein coupled receptor 54HumanProteoliposomePL09710 µg, 50 µg ,100 µg45.2 kDa
GPCRsHMOPMu-type opioid receptorHumanProteoliposomePL025--
GPCRsMT1Melatonin receptorHumanProteoliposomePL02810µg, 20µg ,100 µg , 200 µg, 500 µg,bulk40 kDa
GPCRsRXFP1Relaxin receptor 1HumanProteoliposomePL06810 µg, 50 µg ,100 µg89.1 kDa
Ion Channelskir1.1bATP-sensitive inward rectifier potassium channel 1 isoform bMouseProteoliposomePL03110µg, 20µg,100 µg, 200 µg, 500 µg, bulk42.7 kDa
Ion Channelskv1.2Potassium voltage-gated channel subfamily A, member 2RatProteoliposomePL03710µg, 20µg ,100 µg , 200 µg, 500 µg,bulk57 kDa
Ion Channelskv1.3Potassium voltage-gated channel subfamily A, member 3MouseProteoliposomePL03610µg, 20µg ,100 µg , 200 µg, 500 µg,bulk58 kDa
Ion ChannelsVDAC1Voltage-Dependent Anion Channel 1HumanProteoliposomePL02910 µg, 50 µg ,100 µg30.7kDa
Ion ChannelsVDAC1 – DetergentVoltage-Dependent Anion Channel 1HumanDetergentD02910 µg, 50 µg, 100 µg30.7kDa
LigandsSDF1aStromal cell-derived factor 1HumanSolubleS06910 µg, 50 µg ,100 µg10.7 kDa
PorinsOEP24Outer envelope pore protein 24, chloroplasticPlantProteoliposomePL04010 µg, 50 µg ,100 µg24 kDa
PorinsOprFOuter membrane porin FBacteriaProteoliposomePL04510 µg, 50 µg, 100 µg40 kDa
Enzymesgp91phox (Nox2 subunit)gp91phoxHumanProteoliposomePL00810µg, 20µg ,100 µg , 200 µg, 500 µg,bulk55 kDa
EnzymesKMOKynurenine 3-monooxygenaseHumanProteoliposomePL00510µg, 20µg ,100 µg , 200 µg, 500 µg,bulk55,8 kDa
EnzymesNox2, p22 PhoxCytochrome b-245 light chainHumanProteoliposomePL03910 µg, 50 µg ,100 µg23,5 kDa
EnzymesNox4Nox4HumanProteoliposomePL05910µg, 20µg ,100 µg , 200 µg, 500 µg,bulk67 kDa
EnzymesPORCNProtein-Cysteine N-palmitoyltransferase porcupineHumanProteoliposomePL00610 µg, 50 µg, 100 µg55.5 kDa
EnzymesTFTissue factorHumanProteoliposomePL05310µg, 20µg ,50µg, 100 µg , 200µg, 500 µg,bulk33 kDa
EnzymesT7 RNA PolT7 RNA PolymeraseBacteriophage T7SolubleS19210 µg, 50 µg, 100µg100.1 kDa
EnzymesDsbCDisulfide bond isomeraseE.coliSolubleS197customized quantity on request.25.4 kDa
ReceptorsCLDN 18.2Claudin 18.2 ProteinHumanProteoliposomePL11910 µg, 50 µg, 100 µg30 kDa
Transcriptional regulatorsAROSActive regulator of SIRT1HumanProteoliposomeS05210µg, 20µg ,100 µg , 200 µg, 500 µg,bulk15,4 kDa
TransportersBakBcl-2 homologous antagonist killerHumanProteoliposomePL03825µg ,100 µg ,500 µg,bulk17 kDa
TransportersEspHCytoskeleton-modulating effector of enterohaemorrhagic and enteropathogenic Escherichia coliBacteriaProteoliposomePL05110 µg, 50 µg, 100 µg21.9 kDa
TransportersHCV p7Hepatitis C virus P7VirusProteoliposomePL04225µg ,100 µg ,500 µg,bulk7 kDa
TransportersNhaANa(+)/H(+) antiporter NhaAE. coliProteoliposomePL03210 µg, 50 µg, 100 µg43.9 kDa
TransportersUCP1Mitochondrial brown fat uncoupling protein 1MitochondriaProteoliposomePL04710 µg, 50 µg, 100 µg35.1 kDa
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AxisPharm是一家专业的分析服务提供商,致力于为科学研究界和工业界提供高质量的分析服务。凭借先进的仪器设备和专业的技术团队,AxisPharm在生物分析、化学分析和质量控制领域树立了良好的声誉。AxisPharm公司的产品线包括:PEG 连接子、用于药物递送的脂质、荧光染料、单击化学试剂、聚聚乙二醇,共聚物、可裂解的连接子、抗体和抗体药物偶联物ADC、ADC 有效载荷、细胞生物学试剂、脱氧核糖核酸、修饰语、探针、合成肽、目标特定链接器、硫醇反应性接头、酸反应性连接子、胺反应性连接子、羰基反应性连接子、探针、修饰符。


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AxisPharm产品线

PEG连接子:聚合物聚乙二醇是多分散聚乙二醇 (PEG) 聚合物,是一种从石油中提取的聚醚化合物,具有从工业制造到医药的许多应用。

● 用于药物递送的脂质:在药物递送系统中起着至关重要的作用,特别是在脂质体、脂质纳米颗粒或脂质胶束等脂质制剂中。脂质提供结构稳定性,增强药物溶解度,实现控释,并促进靶向药物递送。

● 荧光染料:也称为荧光团或荧光探针,是吸收一种波长的光并以更高波长发射的化合物,从而产生可见荧光。它们是生物学研究中的重要工具,用于标记和检测蛋白质、核酸和细胞等生物分子,从而在显微镜、流式细胞术和实时荧光定量 PCR 等应用中实现灵敏和精确的可视化。

● 点击化学试剂:具有高特异性和最少的副产物,简化了复杂的合成过程。因此,它们在分子生物学、材料科学和药物化学中发挥着至关重要的作用。

● 聚合物聚乙二醇:多分散聚乙二醇 (PEG) 聚合物,是一种从石油中提取的聚醚化合物,具有从工业制造到医药的许多应用。

● 可裂解连接子:一类重要的分子,广泛应用于药物发现、化学生物学和材料科学等各个领域。这些连接子充当两个或多个分子实体之间的连接桥,可以在特定条件下选择性地裂解,从而释放附着的分子。这一特性使它们成为生物活性化合物靶向药物递送、成像和控释的有吸引力的工具。

● 抗体及抗体-药物偶联物及细胞生物学试剂种类丰富可选择。

● ADC有效载荷:作为 ADC 的三个主要成分之一,有效载荷是高活性和有毒的药物分子,通过化学连接子附着在抗体上。有效载荷可以是小分子、蛋白质毒素、生物活性肽、酶,甚至放射性核素。通过适当的接头与适当的载体系统耦合的有效载荷可能会显示出靶向药物递送的特异性和有效性的提高。

● 脱氧核糖核酸:DNA 是脱氧核糖核酸的缩写,是一种包含所有生物体发育和功能的遗传指令的分子。DNA 由四个基本组成部分组成,称为核苷酸,由糖、磷酸基团和含氮碱基组成。

● 改性剂:改变其他分子或材料特性的化合物。在药物研发领域,改性剂在新型药物递送系统和生物医学设备的设计和优化中发挥着至关重要的作用。一种常见的改性剂类型是官能团,它是赋予分子特定化学和物理性质的原子的特定排列。

● 探针:AxisPharm 提供各种靶标特异性探针,例如叶酸 PEG、生物素 PEG、PROTAC PEG、荧光染料探针和图像探针。探针是一类含有官能团的化合物,旨在选择性地与生物分子(如酶、受体和核酸)相互作用。这些官能团包括荧光染料、生物素和亲和标签等,可以检测和定量复杂生物系统中的特定分子。


Different Types of Polyethylene Glycol PEG Linkers in Stock
Acid PEGDiketone PEGNon-PEG linkerPFP ester PEGSugar PEG β-Glucuronide Linker
Aldehyde PEGDNP PEGPEG-t-butyl esterPhosphonate PEGSulfonic acid PEG
Alkyne PEGDBCO PEGPEG-X-PEGPolymer PEGTCO PEG
Amino PEGDSPE PEGPeptide LinkersPropargyl PEGTetrazine PEG
Aminooxy PEGFluorescent PEGLipid PEGPROTAC LinkerHomobifunctional PEG
Azide PEGFmoc PEGM-PEGSilane PEGBromo PEG
BCN-PEGFolate PEGMaleimide PEGSPDP PEGTosylate PEG
Benzyl-PEGThiol PEGMeNH-PEGBranched PEGBis-Sulfone PEG
Biotin PEGHydrazide PEGNHS ester PEGHyNic PEGDOTA Reagent DOTA PEG
Bis-PEG-acidHydroxy PEGBoc-PEGBis-PEG-NHSIodo PEG
Bis-PEG-NHSCleavable Linkers


Lipids for Drug Delivery
Biotinyl Cap PEDodecanyl PEOther LipidPhosphatidylcholinePhosphatidylethanolamine
Biotinyl PEGlutaryl PEPDP PEPhosphoglycerolPtd Thioethanol
Caproylamine PEIonizable LipidPE MCCPhosphoserineSuccinyl PE
Cationic LipidLipid PEGCyanur PEMPB PE
Fluorescent Dye
AF DyesCyanine DyesMB DyesRhodamine DyeRox (carboxy-X-rhodamine) Dye
APDye FluorsDNP PEGJOER6GPeptide Labeling Reagents
Bodipy ProbesFluorescein (FAM)Pyrene ProbesTAMRA DyeClassic Fluorescent Dyes
IR FluorsQuenchersCoumarin 343

Click Chemistry Tools & Reagents
Alkyne PEGBCN-PEGPTAD LinkerTetrazine PEGClick Chemistry Auxiliary Reagents
Azide PEGDBCO PEGTCO PEGMethylcyclopropene Linkers
Polymer PEG
AcrylateBiotinFmocLipoamideSilane
Active esterBocFolateMaleimideStearic acid
AldehydeCarboxylic acidguanlian1010MW 2000TCO
AmineCholesterolHydrazideMW 5000Thiol
AzideDBCOHydroxylPolysarcosine
Cleavable Linkers
-S-S-CleavablePC CleavableDisulfide LinkersDde Cleavable Linkersβ-Glucuronide Linkers
Cleavable Peptidediazo biotin probesDTSSP crosslinkerPhotocleavable Biotin
Antibody and Antibody Drug Conjugate (ADC)
InotuzumabTrastuzumabEnfortumabLabetuzumab govitecanMirvetuximab soravtansine (solution)
VobramitamabDisitamabMirzotamabLoncastuximab tesirineTrastuzumab deruxtecan (solution)
PolatuzumabOzuriftamabBrentuximabTrastuzumab deruxtecanADC Control Human IgG1-Deruxtecan (DAR 8)
GemtuzumabInebilizumabDatopotamabCofetuzumab pelidotinGlembatumumab vedotin
Daratumumab (PBS)DenintuzumabSacituzumab govitecanBelantamab mafodotinTrastuzumab duocarmazine
PraluzatamabNaratuximabTisotumabEnfortumab vedotin-ejfvTrastuzumab emtansine (solution)
LorvotuzumabRolinsatamabTrastuzumab emtansineTelisotuzumab vedotinEnfortumab vedotin-ejfv (solution)
IzeltabartMipasetamabDatopotamab deruxtecanGemtuzumab ozogamicinBrentuximab vedotin (solution)
LupartumabIladatuzumabORM-5029Cantuzumab ravtansineDepatuxizumab mafodotin
CantuzumabBriobaceptIfinatamab deruxtecanTusamitamab ravtansineADC Control Human IgG1-Deruxtecan (DAR 4)
LonigutamabTamrintamabTisotumab vedotinZilovertamab vedotinDepatuxizumab MMAE
MoxetumomabSacituzumabDisitamab vedotinPolatuzumab vedotinADC Control Human IgG1-vcMMAF
AzintuxizumabUpifitamabBelantamabPivekimabSacituzumab govitecan (solution)
LifastuzumabGlembatumumabPatritumab deruxtecanFarletuzumab ecteribulin
Payloads and Linker modified Payloads
ExatecanBelotecan HClSGD-1882Dolastatin 10MC-Val-Cit-PAB-Doxorubicin
SN 38GimatecanMMAFCalicheamicinGly3-Val-Cit-PAB-MMAE
AmrubicinTaltobulinAuristatin EEribulin MesylateSuO-Glu-Val-Cit-PAB-MMAE
Mitomycin CDxdChlorambucilSoblidotin (Auristatin PE)Fmoc-G-amino-CH2O acetyl-Exetecan
Deruxtecan analogLurtotecanPF-06380101Deruxtecan analog 2DM1-MCC-PEG3-Biotin
sulfo-SPDB-DM4Exatecan mesylateAuristatin FPaclitaxelGGFG-amino-CH2O-acetyl Exetecan
RubitecanMC-DM1MMAF-methyl esterMC-MMD10Mal-PEG8-Val-Cit-PAB-MMAE
(4-NH2)-ExatecanIrinotecanDoxorubicin-SMCCSPDB-DM4DBCO-PEG4-Val-Cit-PAB MMAF
TopotecanPNU-159682MMAD10-HydroxycamptothecinTopotecan Hydrochloride
CL2A-SN38DM47-Ethylcamptothecin

Cell Biology Reagents
Neuro-DiO, lipophilic tracerVU (5-Vinyl-uridine)CM-DiI, lipophilic tracerLumiTracker ER GreenER-Tracker Red (BODIPY TR Glibenclamide)
Annexin V-AF 647 conjugateDAPI, blue fluorescent nucleic acid stainPropidium IodideDeep-Red Fluorescent Nissl StainMitoCLox, mitochondrial lipid peroxidation probe
Annexin V-AF 488 conjugateLumiTracker Mito Rhodamine 123LumiTracker Mito Green FMRAPID DiI, lipophilic tracerLaurdan (6-Dodecanoyl-2-dimethylaminonaphthalene)
Annexin V, His TagThiazole OrangeSynaptoProbe® RedLumiTracker ER RedLinear Polyacrylamide for Nucleic Acid Precipitation
DiD, lipophilic tracerRH 237, potentiometric probeSynaptoProbe® GreenRAPID DiO, lipophilic tracerFluo-4 AM, green fluorescent calcium indicator
DiR, lipophilic tracerHoechst 33342, blue fluorescent nucleic acid stainLumiTracker® Mito Red FMDiI, lipophilic tracerYODi-1, green fluorescent nucleic acid stain
DNA
CPG solid supportsDNA StainsModified Triphosphatesphosphoramidite
Probes
Biotin PEGFolate PEGImage ProbesPROTAC Linker
Amine reactive Linkers
Acid PEGAldehyde PEGBromo PEGMaleimide PEGNHS ester PEG


AxisPharm提供的服务

● 蛋白质组学服务:提供质谱分析、蛋白质鉴定和定量服务。专注于生物标志物分析,帮助客户在复杂的生物样本中发现和验证潜在的生物标志物。

● 代谢组学服务:利用先进的LC-MS/MS技术进行代谢物分析,提供通路洞察,帮助客户理解代谢途径和生物过程。

● 高级LC-MS/MS服务:用于PK分析和HPLC分离,确保高精度和高效率的研究结果,提供PK/PD研究,支持药物开发和临床前研究。


AxisPharm部分产品列表


Cat#NameM.W.Purity
AP15197Exatecan435.45≥98%
AP15072SN 38392.4≥95%
AP15226Amrubicin483.47≥98%
AP15664Mitomycin C334.3≥98%
AP1520310-Hydroxycamptothecin364.35≥95%
AP152047-Ethylcamptothecin376.41≥95%
AP15210Rubitecan393.35≥95%
AP15211(4-NH2)-Exatecan403.43≥95%
AP15206Topotecan421.5≥95%
AP15207Topotecan Hydrochloride425.5≥95%
AP15202Belotecan HCl433.5≥95%
AP15208Gimatecan447.5≥95%
AP15227Taltobulin473.65≥99%
AP15201Dxd493.48≥95%
AP15209Lurtotecan518.56≥95%
AP15196Exatecan mesylate531.55≥98%
AP15200Deruxtecan analog 2579.58≥95%
AP15205Irinotecan586.68≥95%
AP15224PNU-159682641.62≥98.24%
AP15220Soblidotin (Auristatin PE)701.98≥95%
AP15225SGD-1882725.8≥98%
AP15213MMAF732≥95%
AP15216Auristatin E732≥95%
AP15311Chlorambucil304.21≥98
AP15219PF-06380101743.01≥95%
AP15214Auristatin F746≥95%
AP15215MMAF-methyl ester745.99≥98%
AP15187Doxorubicin-SMCC762.8≥98%
AP15217MMAD771.06≥98%




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