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艾美捷科技代理Magtivio品牌磁珠产品


荷兰Magtivio BV是一家磁性微/纳米颗粒生产商,为生命科学和生物分析领域提供磁珠及完整试剂盒产品。Magtivio BV设计开发了两种类型的二氧化硅包覆氧化铁磁珠,其中包括:超顺磁

性磁珠,它们采用复合多孔结构设计,易于再悬浮,并表现出较低的沉降率;以及铁磁性磁珠,这些磁珠粒型由相对致密的核壳结构制成,具有强磁性,更适合大体积和粘性样品。末端官能

化的基团可以连接到两种磁珠类型的二氧化硅涂层。Magtivio BV的产品包括:


(1)核酸纯化:MagSi-(D)NA试剂盒和磁珠作为固体支持相,从病原体、植物和动物组织、体液和细胞中分离核酸。

(2)DNA纯化:MagSi试剂盒,用于测序应用中的PCR 纯化、DNA大小选择。

(3)免疫测定:MagSi链霉亲和素珠用作固相,易于结合生物素化的生物分子。

(4)蛋白质分析:具有改性表面的MagSi微珠,用于蛋白质的纯化和分离,用于质谱、蛋白质组学分析和生物标志物研究。

(5)研究工具:表面活化的MagSi微珠,用于固定蛋白质、肽、核酸或其他感兴趣的分子;MagSi 平台具有广泛的功能化可能性。

(6)LCMS样品制备:在LC-MS/MS分析之前,基于MagSiMUS磁珠的生物样品制备,用于蛋白质耗竭和从生物样品中去除其他干扰化合物。

(7)SafeQ:用于样本采集、储存和释放的解决方案,例如唾液采集试剂盒

(8)磁选机:用于从液体样品中磁分离MagSi和MagSiMUS磁珠。

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Dendritics.jpg

Dendritics公司主要关注人类树突状细胞,希望找到能够促使CD34+造血前体细胞转化为树突状细胞(在GM-CSF和TNF-alpha存在的情况下)的细胞因子。在1992-2005年间,大量的研究使得研究者对人类树突状细胞的产生、细胞通路、C-type凝集素受体的功能及Toll-like受体的活性有了更深的理解。

 

DENDRITICS was started in 2005 by former members of SCHERING PLOUGH Laboratory for Immunological Research (LIR) in Dardilly, France. From their long experience at LIR, the team members of DENDRITICS have gathered complementary scientific and technological knowledge in different areas of immunology. The initial focus of LIR was in the biology of B lymphocytes, elaboration of human monoclonal antibodies, and in cytokine discovery (IL-3, IL-4, IL-7, IL-10, IL-17, GM-CSF) together with our colleagues of DNAX Research Institute in Palo Alto, California.

 

Our interest in cytokines led to the finding that human dendritic cells (DCs) could be generated in vitro from CD34+ hematopoietic progenitors cultured in the presence of GM-CSF and TNF-alpha.

 

The period from 1992 to 2005 saw the specialization of LIR in DC biology and was fuelled by a large-scale effort to discover and study the function of genes specifically expressed by these cells. This program led to a number of findings that contributed in particular to understanding the heterogeneity of DCs, the pathways regulating DC migration, the function of C-type lectin receptors in DCs and the activity of Toll-like receptors in DCs. Many novel genes were discovered through screening of cDNA libraries or through monoclonal antibodies raised against DCs.

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