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Mirus Bio.jpg

Mirus Bio公司是世界上最早开发高效、低细胞毒性转染试剂的公司之一,同时也是目前该类试剂最主要的供应商之一。Mirus Bio的大部分转染试剂可以在含有血清的培养基中进行转染,省去了更换培养基的麻烦。TransIT-L1是Mirus产品的王牌,自1995年开发出来就申请了美国专利(US 5,744,335)。该项专利技术后来License给了Roche公司,以Fugene 6的品牌对外销售。TransIT-TKO & siQUEST转染试剂是常规siRNA转染试剂的王牌,与脂质体介导的转染试剂相比,该转染试剂可以高效转染siRNA,并且极大地降低了细胞的损伤程度。该试剂与siRNA混合转染细胞时,可以特异性剔除某些基因的表达,用于siRNA介导的基因沉默现象的研究。TransIT-Oligo转染试剂是即用型试剂,可以高效地将各种类型的寡聚核苷酸和寡聚脱氧核苷酸转染至受体细胞中。

 

此外,Mirus Bio还开发了专门针对特殊细胞的体外转染试剂,例如分别针对Jurkat,COS,3T3等细胞的转染试剂。Mirus Bio的科学家们新近开发了一种新的DNA转染试剂:TransITTM-2020 Transfection Reagent。TransITTM的性能优于FuGENETM、LipofectamineTM 2000和 LipofectamineTM 2000 CD;可在多种类型的细胞(包括难转染细胞)中实现高表达。

 

Mirus was founded on the principle that non-viral (i.e. plasmid DNA based) methods offer distinct advantages over viral methods of gene transfer. Our initial breakthrough in 1996 came with the development of a new type of transfection reagent that combined high efficiency delivery with low cellular toxicity: TransIT®-LT1 (Low Toxicity) Reagent remains the “gold standard” for broad-based gene delivery applications.

 

Mirus Bio公司主要产品:

Transfection with TransIT

Ingenio® Electroporation

Virus Production

Labeling with Label IT®

In Vivo Delivery

Accessory Products


品名货号
Human IgG1 Expression Control – 100 ugMIR 6250
Ingenio EZporator Electroporation SystemMIR 51000
Label IT Nucleic Acid Labeling Kit, Amine – sufficient for modifying 25 µg of nucleic acidMIR 3925
Label IT Nucleic Acid Labeling Kit, Amine – sufficient for modifying 100 µg of nucleic acidMIR 3900
TransIT-2020 Transfection Reagent – 0.4 mLMIR 5404
TransIT-2020 Transfection Reagent – 1.0 mLMIR 5400
TransIT-2020 Transfection Reagent – 10 X 1.0 mLMIR 5406
TransIT-2020 Transfection Reagent – 5 X 1.0 mLMIR 5405
TransIT-293  Transfection Reagent – 0.4 mLMIR 2704
TransIT-293 Transfection Reagent – 1.0 mLMIR 2700
TransIT-293 Transfection Reagent – 10 X 1.0 mLMIR 2706
TransIT-293 Transfection Reagent – 5 X 1.0 mLMIR 2705
TransIT-CHO  Transfection Kit – 10 X 1.0 mLMIR 2176
TransIT-CHO  Transfection Kit – 5 X 1.0 mLMIR 2175
TransIT-CHO Transfection Kit – 1.0 mLMIR 2170
TransIT-HeLaMONSTER Transfection Kit – 0.4 mLMIR 2904
TransIT-HeLaMONSTER Transfection Kit – 1.0 mLMIR 2900
TransIT-HeLaMONSTER Transfection Kit – 10 X 1.0 mLMIR 2906
TransIT-HeLaMONSTER Transfection Kit – 5 X 1.0 mLMIR 2905
TransIT-Insect Transfection Reagent – 0.4 mLMIR 6104
TransIT-Insect Transfection Reagent – 1.0 mLMIR 6100
TransIT-Insect Transfection Reagent – 10 X 1.0 mLMIR 6106
TransIT-Insect Transfection Reagent – 5 X 1.0 mLMIR 6105
TransIT-Jurkat Transfection Reagent – 0.4 mLMIR 2124
TransIT-Jurkat Transfection Reagent – 1.0 mLMIR 2120
TransIT-Jurkat Transfection Reagent – 10 X 1.0 mLMIR 2126
TransIT-Jurkat Transfection Reagent – 5 X 1.0 mLMIR 2125
TransIT-Keratinocyte Transfection Reagent – 0.4 mLMIR 2804
TransIT-Keratinocyte Transfection Reagent – 1.0 mLMIR 2800
TransIT-Keratinocyte Transfection Reagent – 10 X 1.0 mLMIR 2806
TransIT-Keratinocyte Transfection Reagent – 5 X 1.0 mLMIR 2805
TransIT-LT1 Transfection Reagent – 0.4 mLMIR 2304
TransIT-LT1 Transfection Reagent – 5 X 1.0 mLMIR 2305
TransIT-mRNA Transfection Kit – 0.4 mLMIR 2225
TransIT-mRNA Transfection Kit – 1.0 mLMIR 2250
TransIT-mRNA Transfection Kit – 10 X 1.0 mLMIR 2256
TransIT-mRNA Transfection Kit – 5 X 1.0 mLMIR 2255
TransIT-Oligo Transfection Reagent – 0.4 mLMIR 2164
TransIT-Oligo Transfection Reagent – 1.0 mLMIR 2160
TransIT-Oligo Transfection Reagent – 10 X 1.0 mLMIR 2166
TransIT-Oligo Transfection Reagent – 5 X 1.0 mLMIR 2165
TransIT-PRO Transfection Kit – 1.0 mL (with boost)MIR 5700
TransIT-PRO Transfection Kit – 10 mL (with boost)MIR 5760
TransIT-PRO Transfection Reagent – 1 mL (without boost)MIR 5740
TransIT-PRO Transfection Reagent – 10 mL (without boost)MIR 5750
TransIT-siQUEST Transfection Reagent – 0.4 mLMIR 2114
TransIT-siQUEST Transfection Reagent – 1.5 mLMIR 2110
TransIT-siQUEST Transfection Reagent – 10 X 1.5 mLMIR 2116
TransIT-siQUEST Transfection Reagent – 5 X 1.5 mLMIR 2115
TransIT-TKO Transfection Reagent – 0.4 mLMIR 2154
TransIT-TKO Transfection Reagent – 1.5 mLMIR 2150
TransIT-TKO Transfection Reagent – 10 X 1.5 mLMIR 2156
TransIT-TKO Transfection Reagent – 5 X 1.5 mLMIR 2155
TransIT-X2 Dynamic Delivery System – 0.3 mLMIR 6003
TransIT-X2 Dynamic Delivery System – 0.75 mLMIR 6004
TransIT-X2 Dynamic Delivery System – 1.5mLMIR 6000
TransIT-X2 Dynamic Delivery System – 10 X 1.5 mLMIR 6006
TransIT-X2 Dynamic Delivery System – 5 X 1.5 mLMIR 6005
Ingenio Electroporation Accessory – Cell Droppers (50 pk)MIR 50125
Ingenio Electroporation Solution Only – 25 rxns (6.25 mL)MIR 50111
Label IT Nucleic Acid Labeling Kit, Biotin – labels 100 µg nucleic acidMIR 3400
Label IT Plasmid Delivery Control, Cy3 – 10 µgMIR 7904
Label IT RNAi Delivery Control, Cy3 – 10 µg (0.75 nmol)MIR 7900
TransduceIT Transduction Reagent – 1 mLMIR 6620
TransIT-BrCa Reagent Transfection Reagent – 0.4 mLMIR 5504
Ingenio Electroporation Accessory – 0.4 cm Cuvettes (50 pk)MIR 50123
Ingenio Electroporation Solution Only – 50 rxns (12.5 mL)MIR 50114
Label IT Nucleic Acid Labeling Kit, Biotin – labels 25 µg nucleic acidMIR 3425
Label IT Plasmid Delivery Control, Cy3 – 100 µgMIR 7905
Label IT RNAi Delivery Control, Cy3 – 100 µg (7.5 nmol)MIR 7901
Label IT siRNA Tracker Intracellular Localization Kit, CX-Rhodamine – labels 50 µg siRNAMIR 7214
Label IT Tracker Intracellular Nucleic Acid Localization Kit, CX-Rhodamine – labels 50-200 µg plasmid DNAMIR 7022
Lentivirus Packaging Mix – 34 rxnMIR 6640
TransIT-BrCa Reagent Transfection Reagent – 1.0 mLMIR 5500
TransIT-LT1 Transfection Reagent – 1.0 mLMIR 2300
Ingenio Electroporation Accessory – 0.2 cm Cuvettes (50 pk)MIR 50121
Ingenio Electroporation Solution Only – 100 rxns (25 mL)MIR 50117
Label IT Nucleic Acid Labeling Kit, CX-Rhodamine – labels 100 µg nucleic acidMIR 3100
Label IT Plasmid Delivery Control, Fluorescein – 10 µgMIR 7906
Label IT RNAi Delivery Control, Fluorescein – 10 µg (0.75 nmol)MIR 7902
Label IT siRNA Tracker Intracellular Localization Kit, Cy3 – labels 50 µg siRNAMIR 7212
Label IT Tracker Intracellular Nucleic Acid Localization Kit, Cy3 – labels 50-200 µg plasmid DNAMIR 7020
Lentivirus Packaging Mix – 5 rxnMIR 6630
TransIT-BrCa Transfection Reagent – 5 x 1.0 mLMIR 5505
Ingenio Electroporation Kit, for Amaxa – 25 rxns (0.2 cm Cuvettes/Droppers)MIR 50112
Label IT Nucleic Acid Labeling Kit, CX-Rhodamine – labels 25 µg nucleic acidMIR 3125
Label IT Plasmid Delivery Control, Fluorescein – 100 µgMIR 7907
Label IT RNAi Delivery Control, Fluorescein – 100 µg (7.5 nmol)MIR 7903
Label IT siRNA Tracker Intracellular Localization Kit, Cy5 – labels 50 µg siRNAMIR 7213
Label IT Tracker Intracellular Nucleic Acid Localization Kit, Cy5 – labels 50-200 µg plasmid DNAMIR 7021
TransIT Lentivirus System – 34 rxnMIR 6655
TransIT-BrCa Transfection Reagent – 10 x 1.0 mLMIR 5506
TransIT-LT1 Transfection Reagent – 10 X 1.0 mLMIR 2306
Ingenio Electroporation Kit, for Amaxa – 50 rxns (0.2 cm Cuvettes/Droppers)MIR 50115
Label IT Nucleic Acid Labeling Kit, Cy3 – labels 100 µg nucleic acidMIR 3600
Label IT siRNA Tracker Intracellular Localization Kit, Fluorescein – labels 50 µg siRNAMIR 7216
Label IT Tracker Intracellular Nucleic Acid Localization Kit, Fluorescein – labels 50-200 µg plasmid DNAMIR 7025
TransIT Lentivirus System – 5 rxnMIR 6650
Ingenio Electroporation Kit, for Amaxa – 100 rxns (0.2 cm Cuvette/Droppers)MIR 50118
Label IT Nucleic Acid Labeling Kit, Cy3 – labels 25 µg nucleic acidMIR 3625
TransIT-Lenti Transfection Reagent – 10 x 1.5 mLMIR 6606
Ingenio Electroporation Kit, for other Electroporators – 25 rxns, (0.4 cm Cuvettes/Droppers)MIR 50113
Label IT Nucleic Acid Labeling Kit, Cy5 – labels 100 µg nucleic acidMIR 3700
TransIT-Lenti Transfection Reagent – 1.5 mLMIR 6600
Ingenio Electroporation Kit, for other Electroporators – 50 rxns (0.4 cm Cuvettes/Droppers)MIR 50116
Label IT Nucleic Acid Labeling Kit, Cy5 – labels 25 µg nucleic acidMIR 3725
TransIT-Lenti Transfection Reagent – 0.75 mLMIR 6604
Ingenio Electroporation Kit, for other Electroporators – 100 rxns (0.4 cm Cuvette/Droppers)MIR 50119
TransIT-Lenti Transfection Reagent – 5 x 1.5 mLMIR 6605
TransIT-Lenti Transfection Reagent – 0.3 mLMIR 6603
Label IT Nucleic Acid Labeling Kit, DNP – labels 100 µg nucleic acidMIR 3800
Label IT Nucleic Acid Labeling Kit, DNP – labels 25 µg nucleic acidMIR 3825
Label IT Nucleic Acid Labeling Kit, Fluorescein – labels 100 µg nucleic acidMIR 3200
Label IT Nucleic Acid Labeling Kit, Fluorescein – labels 25 µg nucleic acidMIR 3225
Label IT Nucleic Acid Labeling Kit, MFP488 – labels 100 µg nucleic acidMIR 7100
Label IT Nucleic Acid Labeling Kit, MFP488 – labels 25 µg nucleic acidMIR 7125
TransIT-EE Delivery Solution – 40 InjectionsMIR 5340
TransIT-QR Delivery Solution – 40 InjectionsMIR 5240
pLIVE Vector – 20 ugMIR 5420
pLIVE Vector/LacZ – 20 ug of each vectorMIR 5520
pLIVE Vector/SEAP Control Vector Kit – 20 ug of each vectorMIR 5620
pLIVE Vector Complete System – 20 ug of each vectorMIR 5320
RevIT AAV Enhancer – 1.5 mL (for 1 L of cell culture)MIR 8000
TransIT-VirusGEN GMP Transfection Reagent – 150 mLMIR 6845-GMP
VirusGEN AAV Transfection Kit – 150mLMIR 6755
VirusGEN AAV Transfection Kit, 1 Kit – for 10 L of cell cultureMIR 6745
RevIT AAV Enhancer – 10 x 1.5 mL (for 10 L of cell culture)MIR 8006
RevIT AAV Enhancer – 75 mL (for 50 L of cell culture)MIR 8080
VirusGEN GMP LV Transfection KitMIR 6825-GMP
VirusGEN LV Transfection KitMIR 6760
VirusGEN AAV Kit + RevIT for 10L CultureMIR 8008
VirusGEN GMP AAV Transfection KitMIR 6815-GMP
VirusGEN AAV Transfection Kit – 1 Kit for 1 L of cell cultureMIR 6750
VirusGEN AAV Kit + RevIT for 1L CultureMIR 8007
TransIT-VirusGEN Transfection Reagent – 150 mLMIR 6740
TransIT-VirusGEN Transfection Reagent – 30 mLMIR 6720
TransIT-VirusGEN Transfection Reagent – 10 x 1.5 mLMIR 6706
TransIT-VirusGEN Transfection Reagent – 5 x 1.5 mLMIR 6705


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Diarect.jpg

Diarect有着20多年自身抗原研发经验的Liedvogel教授和Hanbruck博士联手创建。1993年Haubruck博士利用杆状病毒/Sf9昆虫细胞表达系统成功的研发出人重组抗原--TPO,6年后Diarect是第一家将人重组TPO引进体外诊断市场的公司。

 

Established in 1998, DIARECT AG is a privately owned biotech company with expertise in developing and establishing standardized large-scale productions of both recombinant and native proteins, including their worldwide distribution. Providing customers with products and services of consistent quality is one of the cornerstones of DIARECT’s business philosophy.

 

DIARECT is not only a leading manufacturer of autoimmune and infectious disease antigens, but also of recombinant allergens. In additon, DIARECT is the exclusive distributor of Surmodics in Europe. With Surmodics' protein stabilization reagents, blockers and BioFX substrates, DIARECT is able to provide most of the critical components for the development of diagnostic end products.

 

Diarect公司的主要产品包括:

Allergens

Autoimmune Disease Antigens

Infectious Disease Antigens

Antigen FAQ

Selected References

Protein Stabilizers / Blockers

Immunoassay Stabilizers

Protein and Conjugate Stabilizers

Microsphere and Microarray Stabilizers

StabilBlot™ Blockers

Protein Stabilizers / Blockers FAQ

Selected References

Immunoassay Substrates

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List Labs.jpg

List Labs公司成立于1978年,位于美国加州硅谷,是一家专业提供各类微生物Toxin的生物技术公司。

 

Our company was founded in 1978 by Linda Shoer. Cholera toxin, the first product, was sought after by those doing research in signal transduction and by others using the toxin B subunit to label neurons. At that time there were no commercial suppliers of this toxin. Our company has always focused on quality bacterial toxins, which you can depend on for your research. Because toxins have been the basis for many vaccines, List Labs products have supported vaccine development. List Labs was the first to commercialize many bacterial toxins for research, including C.difficile toxins and pertussis toxin. Today, we remain uniquely focused on manufacturing, offering and supporting a wide range of bacterial products.

 

List Labs' heart is in the science and the discovery of innovative reagents. Our office is located in Campbell, California, in Silicon Valley. We serve the global research community with an expanding group of distributors. Years of experience translate into expertise in the production, shipment and handling of dangerous goods. If you have questions about any of our products or services, contact us.

 

List Biological Labs的主要产品包括:

Anthrax Toxins

Antisera & Antibodies

Botulinum Toxins

Cholera Toxins

Difficile Toxins

Diphtheria Toxin & Crm

Exotoxin A

Fret Peptides, Native Substrates & Receptors

Lipopolysaccharides

Pertussis Toxins & Virulence Factors

Shiga Toxins

Staphylococcal Toxins

Tetanus Toxins & Related Products

Toxoids

Vaccine Carrier Proteins And Adjuvants

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ViroStat.jpg

ViroStat于1985年,由Douglas McAllister博士创立,致力于为研究者和工业界提供传染性疾病的抗体产品。产品线涵盖病毒学、细菌学和寄生虫学,应用于呼吸道药、性病药、胃肠药/毒素和食源性致病菌的检测。ViroStat拥有超过500种传染性疾病相关的试剂,其中包括MONOTOPE系列单克隆抗体、PMNITOPE多克隆抗体和数量众多的重组蛋白抗原。基于长期的经验积累,ViroStat能够提供从100ug到10g级别的产品。

 

ViroStat was founded in 1985 by Dr. Douglas McAllister to provide infectious disease antibody tools to researchers and manufacturers. These include the areas of virology, bacteriology and parasitology. Applications for these include detection of respiratory agents, STD agents, gastrointestinal agents/toxins and food borne pathogens.

 

The company offers more than 500 infectious disease reagents including their MONOTOPE™ monoclonal antibodies, OMNITOPE™ polyclonal antibodies and numerous recombinant antigens. Many of these antibodies are used by manufacturers of rapid, point of care tests currently made and sold in the US.

 

ViroStat公司产品包括:

MONOTOPE™ - Monoclonal Antibodies (Mouse) 小鼠单克隆抗体

RABMAB® - Monoclonal Antibodies (Rabbit) 兔单克隆抗体

OMNITOPE™ - Polyclonal Antibodies多克隆抗体

RECOMBINANT ANTIGENS 重组抗原

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LC Laboratories.png

LC Laboratories(LC Labs)公司成立于1980年,一直专注于信号转导,肿瘤以及其他临床前试剂的研究和生产,主要提供抗癌物质、酶抑制剂、激活剂和离子通道试剂。LC Labs公司不但拥有大规模的制备液相色谱纯化能力,也开发和优化了大量的具有自主知识产权的低成本高纯度生成方法,其生产的小分子试剂纯度高、价格低和销量大。

 

1980年,LC Labs是PMA(佛波醇12-豆蔻酸 13醋酸;TPA)的全球主要生产商,36年来的销售量超过150,000瓶;1989年为研究试剂市场提供第一个纯度高价格低的毒萝卜素;1990年提供第一个纯度高价格低的冈田酸;1991年提供第一个纯度高价格低的花萼海绵诱癌素A,并且持续是这种广泛使用的磷酸酶抑制剂的全球主要生产商;1995年提供第一个异构体级别纯度的低价格Gö 6976;1996年提供第一个纯度高价格低的罗霉素A1;2002年提供第一个纯度高价格低的雷帕霉素(抗真菌抗生素);同年,提供第一个纯度高、价格低的FK-506;2003年提供第一个纯度高价格低的来普霉素B;2004年提供第一个纯度高价格低的星孢菌素;同年,提供第一个纯度高价格低的环巴胺;2007年,LC Labs公司为临床前肿瘤相关研究引入第一组纯度高价格低的常用蛋白激酶抑制剂。

 

热销产品:

Bortezomib硼替佐米(99%,97%)

Cyclosporine-A环胞霉素A

Cyclopamine环巴胺

17-DMAG,Hydrochloride SaltHSP90抑制剂

Everolimus依维莫司

FK-506他克莫司

Forskolin腺苷酸环化酶激活剂

Gefitinib吉非替尼

Leptomycin B细霉素B 出核转运抑制剂

LY 294002PI3-K抑制剂

PD98059MEK抑制剂

RoscovitineCDK抑制剂

Rapamycin雷帕霉素

SB 202190MAPK抑制剂

SB203580P38MAPK抑制剂

SP600125JNK抑制剂

Staurosporine星孢菌素

UO126MAPK抑制剂

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Polymer Source.jpg

Polymer Source公司成立于1994年,致力于为世界范围的客户提供高品质的Deuterated Polymers 氘代聚合物和Protonated Polymers质子化聚合物。

 

Since its inception in 1994, Polymer Source Inc. takes great pride in supplying a high quality of architecturally controlled specialty polymers in the world of research and development. Our research team comprises of dynamic, competent and innovative scientists who excel in supplying top class service to various research institutions. Within a span of six years our team has accomplished the production of over 3000 block copolymers that have gained worldwide recognition.


image.png

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Polymer Source公司的主要产品包括:

Deuterated Homopolymers 氘代均聚物

Deuterated Block Copolymers 氘代嵌段共聚物

Deuterated Functionlized Polymers 氘代功能聚合物

Deuterated Random and Alternating Copolymers 氘代无规和交替共聚物

Deuterated Monomers 氘代单体

Deuterated Oligomers (Dimer & Trimer etc.) 氘代齐聚物(二聚物和三聚物等)

C13 Labeled Polymers C13标示聚合物

Monomers-High Purity 高纯单体

Hydrophobic Polymers 憎水聚合物

Hydrophilic Polymers 亲水聚合物

Diblock Copolymers 双嵌段共聚物

Amphiphilic Block Copolymers 两性嵌段共聚物

A-B-A Triblock Copolymers A-B-A三嵌段共聚物

A-B-C Triblock Copolymers A-B-C三嵌段共聚物

Random and Alternating Copolymers 无规和交替共聚物

Functionalized Polymers 功能聚合物

Star-like Polymers 星形聚合物

Comb-like Polymers 梳子形聚合物

Labeled Polymers 标示聚合物

Ionomers 离子聚合物

Oligomers (Dimer & Trimer etc.) 齐聚物(二聚物和三聚物等)

Conducting and Luminescence Polymers 导电和荧光聚合物 

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Nanoprobes.jpg

Nanoprobes公司专业生产免疫金标记和免疫测定试验产品。其独特的金标技术使用化学交联的金属和纳米颗粒团簇作为标记。与胶体金颗粒静电吸附在抗体和蛋白质上的传统免疫金探针不同,本公司的金标是与生物分子在特定位点交联的不带电荷的分子。这使我们的探针具有胶体金不具备的范围和灵活性。我们的标记可以附着在任何带有反应基的分子上– 蛋白质、多肽、寡核苷酸、小分子和脂类 - 以检测和定位这些分子。其他标记可以与我们的金标共同使用,我们独特的荧光纳米金探针在一个探针中结合了纳米金(nanogold®)和荧光素,用于荧光和电镜两种技术共同进行样品成像。

 

Nanoprobes was founded in 1990 by Dr. James F. Hainfeld, along with a group of scientists who were also alumni of Brookhaven National Laboratory. The independent research facility they formed has allowed Dr. Hainfeld and his colleagues the freedom to pursue some of the greatest challenges in research: seeking cures for cancer and other diseases.

 

While part of the funding for these endeavors has come from research grants, another source had to be found, as the scientific community faces ever-increasing government cutbacks. To this end, Nanoprobes began to offer many of the nanoparticle technologies developed by its members for use in other scientists' research.

 

Nanoprobes公司主要产品:

AuroVist™ 15 nm & 1.9 nm X-ray Contrast Agent

Conjugates

Enhancement / Developers

EnzMet™ ultra-sensitive

Gold Nanomaterials: Functionalized Nanoparticles

Gold Nanoparticle Reagents

Histadine (His) Tag Labeling

Recombinant Protein Detection

FerroMag™ Magnetic nanoparticles

Negative Stains for EM

Xray Contrast Agents

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